![]() ![]() The Western States Pediatric Environmental Health Specialty Units have developed a number of factsheets to educate immigrant communities on lead and other heavy metal contamination and the risk of exposure from certain imported makeup including kohl, kajal and surma. Reducing Childhood Lead Poisoning in Immigrant Communities from Imported Makeup These resources were developed by various federal, state and local government agencies and partners and do not necessarily represent the views and policies of EPA.Ĭontact us to add additional resources to this list. In addition, some resources contain case and technical reports which may be useful for public health professionals. The resources compiled below are primarily for members of the public who may use these cultural products. Clear your search by clicking reset filters. Using these Resources and Search ToolĬlick on links in the categories below to narrow your search based on the cultural product, type of contaminant, and language. Further narrow the search by using the drop-down menus located on the first row of the table. Learn more about the health effects of mercury exposure. Learn more about the health effects of lead exposure. For example, health impacts from lead exposure in children may include learning difficulties, reduced IQ, and behavioral issues such as hyperactivity and inability to pay attention. However, health impacts can be subtle, and you may not be able to tell just by looking at someone or may take years to present themselves. The presence of heavy metals in these products may come as a surprise to some since these products have been used during their own childhoods and into adulthood without any obvious health impacts. Risks of Heavy Metal ExposureĬultural products can contain heavy metals such as lead, mercury, arsenic, antimony and cadmium. These products include cosmetics, religious powders, spices, traditional medicines, and cookware that may be used by communities in the United States. However, new insight indicates that a combination of low-dosed BAL plus DMPS could be a preferred antidotal therapy to obtain mobilization of the intracerebral deposits into the circulation for subsequent rapid urinary excretion.ĭMPS DMSA EDTA Metal chelators Metals.This webpage compiles educational and outreach materials highlighting the risks from heavy metal exposure primarily to children and people who are pregnant from a variety of cultural and religious products. DMPS and DMSA are also promising antidotes in Hg poisoning, whereas DMPS seems to be a more efficient agent against As poisoning. Anyhow, oral therapy with DMSA should be continued with several intermittent courses. The present paper discusses if a combination of the extracellularly distributed DMSA with the ionophore, Monensin may provide a less toxic combination for Pb mobilization by increasing both the efflux of intracellularly deposited Pb and the urinary Pb excretion. We suggest that BAL in such cases acted as a shuttling Pb transporter from the intra- to the extracellular space. Combination therapy with BAL and CaEDTA was previously recommended in cases of severe acute Pb poisoning with encephalopathy. ![]() Because of its adverse effects, CaEDTA should be replaced by DMSA as the antidote of choice in treating moderate Pb poisoning. DMSA has considerably lower toxicity than the classic heavy metal antagonist BAL (2,3-dimercaptopropanol) and is also less toxic than DMPS. This article reviews the clinical use of the metal chelators sodium 2,3-dimercapto-1-propanesulfonate (DMPS), meso-2,3-dimercaptosuccinic acid (DMSA), and calcium disodium edetate (CaEDTA, calcium EDTA) in overexposure and poisonings with salts of lead (Pb), mercury (Hg), and arsenic (As).
0 Comments
Leave a Reply. |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |